Tetracyclines

Материал из Поле цифровой дидактики



5.00
(1 голос)
Описание Tetracyclines are broad-spectrum bacteriostatic antibiotika. It used to be widely used in pediatrics, but only until it was found to damage tooth enamel and growth cartilage.
Механизм действия Inhibition of proteosynthesis, reversible binding to the 30S subunit of the ribosome .
Спектр действия
  • Broad spectrum, G + and G−, mycoplasmas , chlamydia , spirochetes , some protozoa (amoebae).
  • Many strains are resistant (many G + cocci, G− aerobic rods), resistance is cross-linked.
  • Does not affect Pseudomonas spp., Proteus spp. and Serratia spp.
Фармакокинетика It is preferred after administration, better on an empty stomach.