]> 2026-05-20T16:33:37+03:00 Chlamydia 0 ru Both Chlamydia trachomatis and Chlamydia pneumoniae are Gram-negative (or at least are classified as such, they are difficult to stain, but are more closely related to Gram-negative bacteria), aerobic, intracellular pathogens. They are typically coccoid or rod-shaped and require growing cells to remain viable. Chlamydia cannot synthesize its own ATP, and can also not be grown on an artificial medium, and consequently was once thought to be a virus. The unique cell wall of Chlamydia trachomatis is thought to be one of its virulence factors, as it inhibits phagolysosome fusion in phagocytes. The cell wall contains an outer lipopolysaccharide membrane but lacks peptidoglycan. It instead contains cysteine-rich proteins that are likely the functional equivalent of peptidoglycan. This unique cell wall structure, allows for intracellular division and extracellular survival. The sequences of both Chlamydia trachomatis and Chlamydia pneumoniae have been determined with the hope that a comparison between the two genomes will significantly enhance the understanding of both pathogens. Identification of genes particular to one or the other species could indicate mutually exclusive biological, virulence, and pathogenesis capabilities, while genes the two have in common will help researchers better understand the metabolic capabilities necessary for living in a human host. Bacteria; Chlamydiae/Verrucomicrobia group; Chlamydiae; Chlamydiae (class); Chlamydiales; Chlamydiaceae; Chlamydia Chlamydia muridarum, Chlamydia trachomatis, Chlamydia pneumoniae (also known as Chlamydophila pnemoniae) 2022-09-23T12:29:25Z 2459846.0204282 Chlamydia