Юнусова Юлия в 12:07, 23 сентября 2022

2022-09-23T12:07:24Z

← Предыдущая версия		Версия от 15:07, 23 сентября 2022
Строка 10:		Строка 10:
	* Erythromycin		* Erythromycin
	* Roxithromycin (Rulid, Surlid,Roxid)		* Roxithromycin (Rulid, Surlid,Roxid)
			Вильпрафен Спирамицин

Patarakin: Новая страница: «{{Antibiotics |Description=The macrolides are a group of drugs (typically antibiotics) whose activity stems from the presence of a macrolide ring, a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14, 15 or 16-membered. Macrolides belong to the polyketide class of natural products. |Mechanism of action=The mechanism of action of the macrolides is inhibition of...»

2022-09-22T18:23:11Z

Новая страница: «{{Antibiotics |Description=The macrolides are a group of drugs (typically antibiotics) whose activity stems from the presence of a macrolide ring, a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14, 15 or 16-membered. Macrolides belong to the polyketide class of natural products. |Mechanism of action=The mechanism of action of the macrolides is inhibition of...»

Новая страница

{{Antibiotics
|Description=The macrolides are a group of drugs (typically antibiotics) whose activity stems from the presence of a macrolide ring, a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14, 15 or 16-membered. Macrolides belong to the polyketide class of natural products.
|Mechanism of action=The mechanism of action of the macrolides is inhibition of bacterial protein biosynthesis by binding reversibly to the subunit 50S of the bacterial ribosome, thereby inhibiting translocation of peptidyl tRNA. This action is mainly bacteriostatic, but can also be bactericidal in high concentrations. Macrolides tend to accumulate within leukocytes, and are therefore actually transported into the site of infection.
|Antimicrobial spectrum=Antibiotic macrolides are used to treat infections such as respiratory tract and soft tissue infections. The antimicrobial spectrum of macrolides is slightly wider than that of penicillin, and therefore macrolides are a common substitute for patients with a penicillin allergy. Beta-hemolytic streptococci, pneumococci, staphylococci and enterococci are usually susceptible to macrolides. Unlike penicillin, macrolides have been shown to be effective against mycoplasma, mycobacteria, some rickettsia and chlamydia.
}}
Common antibiotic macrolides
* Azithromycin (Zithromax, Zitromax, Sumamed)
* Clarithromycin (Biaxin)
* Dirithromycin (Dynabac)
* Erythromycin
* Roxithromycin (Rulid, Surlid,Roxid)

Macrolides - История изменений

Юнусова Юлия в 12:07, 23 сентября 2022